Plasma enzymes


Multiple lysosomal hydrolases in plasma

Request a test

To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test.

Additional information

This includes plasma I cell screen (ML II), alpha-mannosidase, beta-mannosidase, beta-glucuronidase, alpha-fucosidase, chitotriosidase, alpha-N-acetylgalactosaminidase, total beta-hexosaminidase and beta-hexosaminicase A. Included in neurological screen

Sending address

Chemical Pathology Reception
Level 1, Camelia Botnar Building
Great Ormond Street Hospital
Great Ormond Street

Laboratory service

Chemical Pathology

Sample requirements

5 ml blood in lithium Heparin blood received at room temperature within 24 hours of phlebotomy or 2 ml of frozen plasma.

Reference range

see report or contact laboratory

Turnaround time

42 days

Disease / group

Mucolipidosis, I-Cell disease, Lysosomal storage disorder


Upon request

Call in advance?

Not required

Chemical Pathology

The Chemical Pathology Laboratory provides an extensive range of services covering both routine biochemistry and specialised analysis and interpretation.

© 2011 Great Ormond Street Hospital for Children NHS Trust