Description
Adenovirus is an important pathogen in both the immunocompetent and immunocompromised host. Infections that can be investigated using this real-time, quantitative polymerase chain reaction (PCR) assay include conjunctivitis, keratoconjunctivitis, upper and lower respiratory tract infection, diarrhoea (and vomiting), myocarditis and haemorrhagic cystitis in children. In the immunocompromised, this assay is used for the regular screening of patients, for the early detection of viraemia. Clinical manifestations in such patients include pneumonia, hepatitis, colitis, meningoencephaliltis and disseminated disease. Viral load can be monitored to evaluate the success of treatment with antivirals or CTLs. This assay has important infection control applications, namely through the rapid diagnosis of respiratory or gastrointestinal infection. Additionally, this assay is used for the environmental screening of cubicles, to determine whether adequate disinfection has removed adenovirus from the environment, thus preventing further transmission. The assay includes an internal control for control of both the nucleic extraction and amplification processes.
Also known as
Request a test
To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test.
Additional information
This assay is duplexed with CMV PCR
Sending address
Microbiology, Virology and Infection Control
Level 4, Camelia Botnar Laboratories
Great Ormond Street Hospital for Children
Great Ormond Street
London
WC1N 3JH
DX number: DX6640203
DX Exchange: Bloomsbury 91WC
Laboratory service
Microbiology, Virology and Infection Control
Sample requirements
Sterile container containing any of the following, as appropriate: EDTA whole blood or plasma (2ml in appropriate blood tube), serum (5ml in clotted blood tube), urine (1ml), NPA, BAL, post-mortem biopsy of any relevant organ, stool, CSF (minimum 200ul) eye swab, nose and throat swab, throat swab (swabs in viral transport medium, available on request). Environmental swabs and the appropriate medium are available on request. Please phone lab to arrange transport.
Reference range
Not applicable
Turnaround time
24 hours
Disease / group
Viral infection
Cost
Upon request
Call in advance?
Please call in advance for environmental swab kit