Parvovirus B19 serology


Parvovirus B19 can cause the childhood infection slapped cheek (or fifth disease), as well as more serious aplastic crisis, persistent anaemia, myocarditis, hepatitis and, rarely, encephalitis. Infection in pregnancy can result in hydrops fetalis. Serological screening by EIA is used to detect IgG and IgM; a positive IgG result is indicative of immunity to infection whereas a positive IgM result suggests current or recent infection. Both IgG and IgM testing is carried out using manual EIA assays. The detection of Parvovirus B19 DNA by PCR is also useful in the diagnosis of infection with this virus.

Also known as

Slapped cheek, fifth disease, erythema infectiosum, hydrops fetalis

Request a test

To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test.

Additional information

Not applicable

Sending address

Microbiology, Virology and Infection Control Level 4, Camelia Botnar Laboratories Great Ormond Street Hospital for Children Great Ormond Street London WC1N 3JH DX number: DX6640203 DX Exchange: Bloomsbury 91WC

Laboratory service

Microbiology, Virology and Infection Control

Sample requirements

Serum (2ml in clotted blood tube)

Reference range

Not applicable

Turnaround time

7 days

Disease / group

Viral infection, viral immunity


Upon request

Call in advance?

Not required

Microbiology, Virology and Infection Control

Our laboratory performs a wide range of routine and specialist investigations in Bacteriology, Virology and PCR.

© 2011 Great Ormond Street Hospital for Children NHS Trust