Streptococcus pyogenes real-time PCR


Streptococcus pyogenes (Group A Strep, GAS) can produce a spectrum of clinical syndromes in humans that range from superficial infection of the pharyngeal mucosa to invasive infection of deep tissues or the blood stream. This real-time PCR assay targets the gene coding for CsrR protein, which is part of a regulatory system that controls expression of several virulence determinants in Streptococcus pyogenes. The GAS-CsrR PCR is multiplexed with an internal control PCR to detect Streptococcus pyogenes DNA in clinical material whilst controlling both the extraction and amplification procedures.

Also known as

S. pyogenes PCR, Strep pyogenes PCR, group A streptococcus PCR, group A strep PCR

Request a test

To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test.

Additional information

This assay is performed as part of a multiplex with S. aureus.

Sending address

Microbiology, Virology and Infection Control Level 4, Camelia Botnar Laboratories Great Ormond Street Hospital for Children Great Ormond Street London WC1N 3JH DX number: DX6640203 DX Exchange: Bloomsbury 91WC

Laboratory service

Microbiology, Virology and Infection Control

Sample requirements

Any sample from a normally sterile site. Respiratory samples. Minimum volume 200 microlitres

Reference range

Not applicable

Turnaround time

24 hours

Disease / group

Bacterial infection


Upon request

Call in advance?

Not required

Microbiology, Virology and Infection Control

Our laboratory performs a wide range of routine and specialist investigations in Bacteriology, Virology and PCR.

© 2011 Great Ormond Street Hospital for Children NHS Trust