Tropheryma whipplei real-time PCR


T. whippeli is a recently characterised bacterium that is the aetiological agent of Whipple�s disease. First characterised by its 16S rDNA sequence, it has been propagated in continuous cell-culture and the entire genome sequenced. Detection of T. whippelii by cell-culture is not practical in a routine diagnostic setting and routine serological assays are not yet available. Amplification of nucleic acid by PCR remains the preferred detection method for this organism. The assay includes an internal control PCR

Also known as

T. whipplei PCR, whipples PCR

Request a test

To request this test please send sample with a request providing patient ID (three identifiers), specimen information, assay required, relevant clinical details and sender information. Before sending sample please read details on requesting and labelling by clicking on the link. Please also refer to any additional information provided for this test.

Additional information

Not applicable

Sending address

Microbiology, Virology and Infection Control Level 4, Camelia Botnar Laboratories Great Ormond Street Hospital for Children Great Ormond Street London WC1N 3JH DX number: DX6640203 DX Exchange: Bloomsbury 91WC

Laboratory service

Microbiology, Virology and Infection Control

Sample requirements

Duodenal biopsies, Blood (EDTA) and CSF. Minimum volume 200 microlitres

Reference range

Not applicable

Turnaround time

24 hours

Disease / group

Bacterial infection


Upon request

Call in advance?

Not required

Microbiology, Virology and Infection Control

Our laboratory performs a wide range of routine and specialist investigations in Bacteriology, Virology and PCR.

© 2011 Great Ormond Street Hospital for Children NHS Trust