Description
Translocation Detection by Reverse transcriptase polymerase chain reaction (RT-PCR). All tests are comlemented by amplification of a relevant housekeeping gene to test the quality of the RNA.Please note that this test is currently not quantitative.
Request a test
When requesting this test please use the referral form provided. Please also refer to any additional information provided for this test.
Additional information
The BCR-ABL p210 transcript is observed in nearly all cases of CML. Philadelphia positive ALL cases are associated with the BCR-ABL p190 transcript as well as a number of CMML cases. The RT-PCR test is currently qualitative.
Sending address
Paediatric Malignancy Unit
Great Ormond Street Hospital for Sick Children
Level 2, Camelia Botnar Laboratories
Great Ormond Street
London
WC1N 3JH
Laboratory service
Specialist Integrated Haematology and Malignancy Diagnostic Service- Acquired Genomics
Sample requirements
5 mls EDTA blood or bone marrow. Please ensure the sample arrives as soon as possible after being taken.
Reference range
Not applicable
Turnaround time
3-5 working days
Disease / group
Chronic Myeloid leukemia
Cost
Upon request
Call in advance?
Please call in advance to discuss requirements