Description
Translocation Detection by Reverse transcriptase polymerase chain reaction (RT-PCR). All tests are designed to amplify PCR products less than 200bp. All tests are comlemented by amplification of a relevant housekeeping gene to test the quality of the RNA.
Request a test
When requesting this test please use the referral form provided. Please also refer to any additional information provided for this test.
Additional information
Alveolar rhabdomyosarocma is a primitive maligant round cell tumour which can occur at any age but primarily in younger children as well as adolescents and young adults. A PAX3-FKHR fusion gene is detected in approximately 70% of cases with a further 10% demonsttrating a variant PAX7-FKHR
Sending address
Paediatric Malignancy Unit
Great Ormond Street Hospital for Sick Children
Level 2, Camelia Botnar Laboratories
Great Ormond Street
London
WC1N 3JH
Laboratory service
Specialist Integrated Haematology and Malignancy Diagnostic Service- Acquired Genomics
Sample requirements
Fresh, frozen or FFPE tissue. If sending FFPE rolled tissue sections please send the equivalent of 80 uM of tissue.
Reference range
Not applicable
Turnaround time
3-5 working days
Disease / group
Rhabdomyosarcoma
Cost
Upon request
Call in advance?
Please call in advance to discuss requirements