Immunology Publications

Translational research of diagnostic techniques:


  • Walshe, D., Gaspar, H.B., Thrasher, A.J., Cale, C.M. and Gilmour, KC. (2009) Signal Transducer and activator of transcription 5 tyrosine phosphorylation for the diagnosis and monitoring of patients with severe combined immunodeficiency.J. Allergy Clin. Immunol.123: 505-508.
  • Wheeler, R.D., Cale, C.M., Cetica, V., Aricò, M. and Gilmour, K.C. (2010) A novel assay for investigation of suspected familial haemophagocytic lymphohistiocytosis.Brit. Journ. Haematol.150: 727-729.
  • Cetica, V., Santoro, A., Gilmour, K.C.,Sieni, E., Pende, D., Marcenaro, S., Koch, F., Grieve, S., Wheeler, R., Zhao, F., zur Stadt, U.,Griffiths, G.M. and Arico, M. (2010) STXBP2 mutations in children with familial haemophagocytic lymphohistiocytosis type 5. J Med Genet. 47: 595-600.


Translational cell therapies:

  • Chatziandreou, I.*, Gilmour, K.C.*, McNicol, A-M, Costabile, M., Sinclair, J., Cubitt, D.,Campbell, J.D.M., Kinnon, C., Qasim, W. and Gaspar, H.B. (2007 ) Capture and Generation of Adenoviral Specific T cells for adoptive immunotherapy.Br. J. Haematol 136:117-126.
  • Qasim, W., Derniame, S., Gilmour, K., Chiesa, R., Weber, M., Adams, S., Rao, K., Amrolia, P., Goulden, N., Very, P. and Gaspar, H. (2011) Third-party virus-specific T cells eradicate adenoviraemia but trigger bystander graft-versus-host disease.Brit. Journ. Haematol.154: 150-3.


Diagnostics and clinical outcome:

  • Booth C, Gilmour KC, Veys P, et al. (2011) X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease. Blood. 6;117(1):53-62.
  • Speckman, C., Pannicke, U., Wiech, E., Schwarz, K., Fisch, P., Friedrich, W., Niehuess, T., Gilmour, K., Buiting, K., Schlesier, M., Eibel, H., Rohr, J., Superti-Furga, A., Gross-Wieltsch U., Ehl, S. (2008) Clinical and immunological consequences of a somatic reversion in a patient with X-linked severe combined immunodeficiency.Blood,112: 4090-4097.
  • Yong, P., Post, F., Gilmour, K.C., King, A., Easterbrook, P., Ibrahim, M.A.A. (2008) Cerebral toxoplasmosis in a middle-aged man as first presentation of primary immunodeficiency due to a hypomorphic mutation in CD40 ligand geneJ. Clin Path,61: 1220-1222.
  • Sharpe LR, Ancliff P, Amrolia P, Gilmour KC, Vellodi A. (2009) Type II Gaucher disease manifesting as haemophagocytic lymphohistiocytosis.J Inherit Metab Dis. #157 e-pub ahead of print



  • Gholam, C., Girgoriadous, S., Gilmour, K.C and Gaspar, H.B. (2011) Familial haemophagocytic lymphohistiocytosis: advances in the genetic basis, diagnosis and management.Clin. Exp. Immunol.163: 271-283.
© 2011 Great Ormond Street Hospital for Children NHS Trust